Bit of a bump, but might be of interest seeing this post hasn't been answered...
I tried the Alone in the Dark Demo: http://www.dosgamesarchive.com/download...-the-dark/
Test card: SB Pro 2.0
Music: Works with setting SB and SB Pro
Effects: Works with SB DMA, SB no DMA. SB Pro option > Blinking cursor, machine locks up
ESS AudioDrive 1868F: Exact same behavior
Now the music isn't Stereo, so I doubt the effects would be Stereo. I wouldn't worry about it and just select Sound Blaster (DMA) for sound effects!